Transform Mechanistic Uncertainty into Decision-enabling Insights
When critical development decisions depend on understanding biological mechanisms, BASF Metabolome Solutions helps uncover the mode of action of bioactive compounds through comprehensive metabolomic profiling. From lead optimization to safety assessment, we deliver the mechanistic insights needed to de-risk development programs, accelerate decision-making, and address complex toxicological questions with confidence.
Turn Complex Biology into Measurable Health Outcomes
Biomarker programs often generate vast amounts of data but limited actionable answers. By combining targeted and untargeted metabolomics with deep scientific expertise, we help you uncover meaningful biological signatures, validate findings, and generate robust evidence that advances research, supports innovation, and accelerates development.
De-Risk Development Through Early Metabolism Insights
Unexpected metabolites and unclear metabolic pathways can create significant development risks. BASF Metabolome Solutions helps you understand how compounds are transformed in biological systems, providing the insights needed to assess safety, optimize candidate selection, and make confident development decisions earlier. Using advanced in-vitro systems or in vivo samples and industrial-grade LC-HRMS analytics, we identify key biotransformation pathways and quantify compound clearance, enabling early risk assessment, confident candidate prioritization, and a faster path to successful development.
MetaMap® Tox helps you move from metabolomics data to confident safety decisions. Built from more than two decades of research by BASF SE and BASF Metabolome Solutions, the database enables early toxicity prediction, mode-of-action investigations, and biological interpretation of compound effects.With over 1,100 reference substances and more than 110 toxicity-associated metabolite signatures, researchers can compare new compounds against an unparalleled knowledge base to identify similarities, evaluate safety risks, and uncover underlying biological mechanisms.
